Automating dicentric chromosome detection from cytogenetic biodosimetry data
نویسندگان
چکیده
منابع مشابه
Automating dicentric chromosome detection from cytogenetic biodosimetry data.
We present a prototype software system with sufficient capacity and speed to estimate radiation exposures in a mass casualty event by counting dicentric chromosomes (DCs) in metaphase cells from many individuals. Top-ranked metaphase cell images are segmented by classifying and defining chromosomes with an active contour gradient vector field (GVF) and by determining centromere locations along ...
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Accurate digital image analysis of abnormal microscopic structures relies on high quality images and on minimizing the rates of false positive (FP) and negative objects in images. Cytogenetic biodosimetry detects dicentric chromosomes (DCs) that arise from exposure to ionizing radiation, and determines radiation dose received based on DC frequency. Improvements in automated DC recognition incre...
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ژورنال
عنوان ژورنال: Radiation Protection Dosimetry
سال: 2014
ISSN: 0144-8420,1742-3406
DOI: 10.1093/rpd/ncu133